Can a chromatic scale have sharps and flats?

Yes, a chromatic scale can have both sharps and flats.

For example, the chromatic scale ascending from C to C# comprises:

- C (no accidental)

- C# (sharp)

- D (no accidental)

- D# (sharp)

- E (no accidental)

- F (no accidental)

- F# (sharp)

- G (no accidental)

- G# (sharp)

- A (no accidental)

- A# (sharp)

- B (no accidental)

- C (no accidental)

Note the presence of both sharps (#) and the natural notes without any accidentals.