* Uma Thurman starred in the film as Ivy, a seductive and manipulative young woman who uses her charm to get what she wants.
* Drew Barrymore played the role of Sylvie, a naive teenager who becomes Ivy's target.
The movie's title references the poisonous plant *Rhus radicans*, commonly known as poison ivy. While the plant itself is not directly featured in the film, the title serves as a metaphor for Ivy's toxic and dangerous nature.
The connection between the actresses and the plant is thus indirect, but it highlights the theme of deception and danger that the movie explores.